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Stock Code 300487
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Solid Phase Peptide Synthesis (SPPS)
Solid Phase Peptide Synthesis (SPPS)
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Fmoc Strategy

Seplife®PS-PEG Sieber resin

  • Seplife®PS-PEG resins consist of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG) is grafted via an ethyl ether group which increases stability towards acid treatment and minimizes PEG leaching. The grafted copolymer shows modified physico-chemical properties which are highly dominated by the PEG moiety and has combined hydrophobic and hydrophilic properties.

    Seplife®PS-PEG Sieber resin contains the Sieber amide (Xanthenyl) linker attached to the resin via an amido bond. It is ideal for the synthesis of partially protected peptide amides. Cleavage is accomplished by treatment with 1% TFA in DCM. As the Sieber linker provides less steric hindrance compared to the Rink handle, bulky building blocks can be attached to the resin easier and with higher yields.
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Products

Properties

Product

Seplife® PS-PEG Sieber Resin

Appearance

Light yellow or yellow beads

Type

Sieber linker

Matrix

Crosslinked polystyrene grafted with polyethylene glycol

 

<0.2

 

0.2-0.3

Substitution (mmol/g)

0.3-0.4

 

0.4-0.5

 

0.5-0.6

Particle size range (micron)

100-250

Shipped as

Dry

 

Transportation

Avoid sunlight, rain, and heavy pressure during transportation. It is strictly forbidden to transport together with toxic and hazardous materials. Product can be shipped at ambient temperature.

Storage

Avoid sunlight, rain, and heavy pressure during transportation. It is strictly forbidden to transport together with toxic and hazardous materials. Product can be shipped at ambient temperature.

Ordering information

Product Name

Product code

Substitution (mmol/g)

 

 

 

Seplife® PS-PEG Sieber Resin

LXHSS06-M-01

<0.2

 

LXHSS06-M-02

0.2-0.3

 

LXHSS06-M-03

0.3-0.4

 

LXHSS06-M-04

0.4-0.5

 

LXHSS06-M-05

0.5-0.6

Production date: See label

Retest period: 1 year, under proper storage conditions

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